| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
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Tetracaine HCl Basic Information:
Pharmaceutical-Grade Anesthetic Purity HCl Powder CAS 136-47-0 - Tetracaine Lidocaine
Lidocaine hydrochloride is swiftly metabolized by the liver, with both metabolites and the unchanged drug being excreted via the kidneys. The biotransformation process encompasses oxidative N-dealkylation, ring hydroxylation, amide linkage cleavage, and conjugation. N-dealkylation, the primary pathway, produces the metabolites monoethylglycinexylidide and glycinexylidide, which have pharmacological and toxicological actions akin to, but less potent than, Lidocaine hydrochloride. Approximately 90% of administered Lidocaine hydrochloride is excreted as various metabolites, with less than 10% excreted unchanged. The main metabolite in urine is a conjugate of 4-hydroxy-2,6-dimethylaniline.
Lidocaine HCl is a powerful amide local anesthetic.
As the dosage increases, its efficacy or potential toxicity also increases, providing an anti-convulsive effect at sub-toxic plasma concentrations.
Blood concentrations exceeding 5μg/ml may induce convulsions.
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