| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
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Tetracaine HCl: Essential Information:
Premium Pharmaceutical Anesthetic - High-Purity HCl Powder | CAS 136-47-0 | Tetracaine & Lidocaine
Lidocaine Hydrochloride undergoes rapid metabolism in the liver, with both metabolites and unchanged drug being excreted primarily through the kidneys. The biotransformation process encompasses oxidative N-dealkylation, ring hydroxylation, amide linkage cleavage, and conjugation. N-dealkylation, a significant metabolic pathway, produces monoethylglycinexylidide and glycinexylidide, which exhibit pharmacological/toxicological effects somewhat akin to Lidocaine Hydrochloride, albeit less potent. Approximately 90% of administered Lidocaine Hydrochloride is excreted as various metabolites, while less than 10% is expelled unchanged. The predominant metabolite present in urine is a conjugate of 4-hydroxy-2,6-dimethylaniline.
Lidocaine HCl: An Amide Local Anesthetic with Proven Efficacy
As dosage increases, both efficacy and potential toxicity amplify. Notably, sub-toxic plasma concentrations exhibit anti-convulsive properties.
Blood concentrations exceeding 5μg/ml can induce convulsions.
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