Tetracaine HCl Basic Information:
Pharmaceutical Anesthetic Purity HCl Powder CAS 136-47-0 Tetracaine Lidocaine
Lidocaine hydrochloride is swiftly metabolized by the liver, with both metabolites and the unchanged drug excreted through the kidneys. The biotransformation process includes oxidative N-dealkylation, ring hydroxylation, amide linkage cleavage, and conjugation. N-dealkylation, a principal pathway, produces the metabolites monoethylglycinexylidide and glycinexylidide, which have pharmacological and toxicological effects similar to, though less potent than, Lidocaine hydrochloride itself. Approximately 90% of administered Lidocaine hydrochloride is expelled as various metabolites, while less than 10% exits the body unchanged. The primary urinary metabolite is a conjugate of 4-hydroxy-2,6-dimethylaniline.
Lidocaine HCl is an amide local anesthetic.
As the dosage increases, both efficacy and toxicity rise, demonstrating an anti-convulsive effect at sub-toxic plasma concentrations.
Blood concentrations surpassing 5μg/ml can induce convulsions.
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Welcome to Wuhan Jingkang Technology Co., Ltd., strategically located in Wuhan, a vibrant city celebrated for its industrious spirit, expansive air transportation network, and stunning landmarks like the historic Yellow Crane Tower.
Through strategic collaborations with numerous domestic universities and research institutes, we have developed a cutting-edge research center. This facility underpins our robust scientific research and stringent quality certification systems. Our steadfast dedication to integrity, quality control, and customer satisfaction has garnered us a stellar reputation both domestically and internationally.
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