| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
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Tetracaine HCl Basic Information:
Pharmaceutical-Grade Anesthetic: Tetracaine HCl Powder, CAS 136-47-0, High Purity for Precision Use
Lidocaine hydrochloride undergoes rapid hepatic metabolism, followed by renal excretion of its metabolites and unchanged forms. Key biotransformation processes include oxidative N-dealkylation, ring hydroxylation, amide linkage cleavage, and conjugation. The primary metabolites, monoethylglycinexylidide and glycinexylidide, exhibit similar but less potent pharmacological/toxicological actions compared to Lidocaine hydrochloride. Approximately 90% of the administered dose is excreted as various metabolites, with under 10% remaining unchanged. The major urinary metabolite is 4-hydroxy-2,6-dimethylaniline conjugate.
Lidocaine HCl: An Effective Amide Local Anesthetic
As dosage increases, both efficacy and toxicity rise, exhibiting an anti-convulsive effect at sub-toxic plasma concentrations.
Blood concentrations exceeding 5μg/ml may induce convulsions.
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