Tetracaine HCl: Essential Information:
Product name |
Tetracaine hcl ( Tetracaine Hrdrochloride) |
CAS No. |
136-47-0 |
Molecular formula |
C15H25ClN2O2 |
Molecular weight |
300.82 |
EINECS number |
205-248-5 |
Melting point |
149°C |
Storage condition |
Room Temperature |
Purity |
>99% |
Standard |
Pharmaceutical Grade |
Appearance |
White or almost white crystal powder |
Pharmaceutical-Grade Anesthetic: High-Purity HCl Powder, CAS 136-47-0 - Tetracaine & Lidocaine
Lidocaine hydrochloride undergoes rapid metabolism by the liver. Both metabolites and the unchanged drug are expelled via the kidneys. The biotransformation process encompasses oxidative N-dealkylation, ring hydroxylation, amide linkage cleavage, and conjugation. The predominant biotransformation route, N-dealkylation, produces monoethylglycinexylidide and glycinexylidide metabolites. These metabolites exhibit pharmacological and toxicological effects similar to but milder than Lidocaine hydrochloride. Approximately 90% of administered Lidocaine hydrochloride is excreted as various metabolites, while less than 10% is excreted unchanged. The primary urinary metabolite is a conjugate of 4-hydroxy-2,6-dimethylaniline.
Lidocaine HCl: An Amide Local Anesthetic
As the dosage increases, both efficacy and toxicity rise, with sub-toxic plasma concentrations demonstrating an anti-convulsive effect.
Blood concentrations exceeding 5μg/ml-1 can induce convulsions.











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