Tetracaine HCl Basic Information:
Product name |
Tetracaine hcl ( Tetracaine Hrdrochloride) |
CAS No. |
136-47-0 |
Molecular formula |
C15H25ClN2O2 |
Molecular weight |
300.82 |
EINECS number |
205-248-5 |
Melting point |
149°C |
Storage condition |
Room Temperature |
Purity |
>99% |
Standard |
Pharmaceutical Grade |
Appearance |
White or almost white crystal powder |
Pharmaceutical Anesthetic Purity HCl Powder CAS 136-47-0 Tetracaine Lidocaine
Lidocaine hydrochloride undergoes rapid metabolism by the liver, with its metabolites and the unchanged drug being excreted via the kidneys. The biotransformation process includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. The major pathway, N-dealkylation, produces the metabolites monoethylglycinexylidide and glycinexylidide, which exhibit pharmacological/toxicological actions similar to but less potent than Lidocaine hydrochloride. Approximately 90% of administered Lidocaine hydrochloride is excreted in various metabolite forms, with less than 10% being excreted unchanged. The primary metabolite found in urine is a conjugate of 4-hydroxy-2,6-dimethylaniline.
Lidocaine HCl is a potent amide local anesthetic, renowned for its effectiveness.
As the dosage increases, both the therapeutic effects and toxicity levels rise, with an anti-convulsive effect observed at sub-toxic plasma concentrations.
Blood concentrations exceeding 5 μg/ml can potentially lead to convulsions.
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