Tetracaine HCl Basic Information:
Product name |
Tetracaine hcl ( Tetracaine Hrdrochloride) |
CAS No. |
136-47-0 |
Molecular formula |
C15H25ClN2O2 |
Molecular weight |
300.82 |
EINECS number |
205-248-5 |
Melting point |
149°C |
Storage condition |
Room Temperature |
Purity |
>99%
|
Standard |
Pharmaceutical Grade |
Appearance |
White or almost white crystal powder |
Pharmaceutical-Grade Anesthetic Purity HCl Powder CAS 136-47-0 - Tetracaine Lidocaine
Lidocaine hydrochloride is swiftly metabolized by the liver, with both metabolites and the unchanged drug being excreted via the kidneys. The biotransformation process encompasses oxidative N-dealkylation, ring hydroxylation, amide linkage cleavage, and conjugation. N-dealkylation, the primary pathway, produces the metabolites monoethylglycinexylidide and glycinexylidide, which have pharmacological and toxicological actions akin to, but less potent than, Lidocaine hydrochloride. Approximately 90% of administered Lidocaine hydrochloride is excreted as various metabolites, with less than 10% excreted unchanged. The main metabolite in urine is a conjugate of 4-hydroxy-2,6-dimethylaniline.
Lidocaine HCl is a powerful amide local anesthetic.
As the dosage increases, its efficacy or potential toxicity also increases, providing an anti-convulsive effect at sub-toxic plasma concentrations.
Blood concentrations exceeding 5μg/ml may induce convulsions.
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