Tetracaine HCl Basic Information:
| Product name |
Tetracaine hcl ( Tetracaine Hrdrochloride) |
| CAS No. |
136-47-0 |
| Molecular formula |
C15H25ClN2O2 |
| Molecular weight |
300.82 |
| EINECS number |
205-248-5 |
| Melting point |
149°C |
| Storage condition |
Room Temperature |
| Purity |
>99% |
| Standard |
Pharmaceutical Grade |
| Appearance |
White or almost white crystal powder |
Pharmaceutical Anesthetic Purity HCl Powder CAS 136-47-0 Tetracaine Lidocaine
Lidocaine hydrochloride is swiftly metabolized by the liver, with both the metabolites and unchanged drug being excreted via the kidneys. The biotransformation process includes oxidative N-dealkylation, ring hydroxylation, amide linkage cleavage, and conjugation. N-dealkylation, the primary biotransformation pathway, produces the metabolites monoethylglycinexylidide and glycinexylidide, which have similar but less potent pharmacological and toxicological effects compared to Lidocaine hydrochloride. Approximately 90% of administered Lidocaine hydrochloride is excreted as various metabolites, with less than 10% excreted unchanged. The primary metabolite found in urine is a conjugate of 4-hydroxy-2,6-dimethylaniline.
Lidocaine HCl is a potent amide local anesthetic.
As the dosage increases, so does its efficacy and potential toxicity. At sub-toxic plasma concentrations, Lidocaine HCl exhibits an anti-convulsive effect.
Blood concentrations exceeding 5μg/ml can induce convulsions.
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